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Side effects are not common, but can include drowsiness, dizziness, headache, nausea, and dry mouth Generic Skelaxin 400 Mg (metaxalone) is a muscle relaxant. The mode of action of this drug has not been clearly identified, but may be related to its sedative properties. If you need to save money on your METAXALONE, compare our prices. Skelaxin is a brand name of metaxalone, approved by the FDA in the following formulation(s): SKELAXIN (metaxalone - tablet;oral) Manufacturer: KING PHARMS Approved Prior to Jan 1, 1982 Strength(s): 400MG (discontinued) Manufacturer: KING PHARMS Approval date: August 30, 2002. These drugs have no direct effect on the muscles or nerves Find drug lifestyle interactions for metaxalone or SKELAXIN. Metaxalone does not directly relax tense skeletal muscles in man METAXALONE (Generic for SKELAXIN) Information En Español What is this medication? 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